GFR reduction and acid retention

wesson.jpgDr. Donald Wesson’s (Texas A&M Health Science Center, Scott and White Healthcare) recent work regarding the potential role of acid retention in increasing plasma levels of aldosterone and endothelin in the setting of moderate chronic kidney disease is the focus of our April 2011 Podcast. Enjoy the conversation between our Editor-in-Chief, Thomas Kleyman and Dr. Wesson as they discuss this exciting work. Accompanying this dialogue, we have an editorial focus written by Dr. Jeffrey Kraut (W. Los Angeles VA) that comments on Dr. Wesson's work.

Donald E. Wesson, Jan Simoni, Kristine Broglio, and Simon Sheather. Acid retention accompanies reduced GFR in humans and increases plasma levels of endothelin and aldosterone. Am J Physiol Renal Physiol 300: F830-F837, 2011.

Editorial Focus

Jeffrey A. Kraut. Effect of metabolic acidosis on progression of chronic kidney disease. Am J Physiol Renal Physiol 300: F828-F829, 2011.