Call for Papers- Aldosterone and Epithelial Na+ Channels

Topic: Aldosterone and Epithelial Na+ Channels

Deadline for Submission: July 1, 2012

The American Journal of Physiology: Renal Physiology is seeking manuscripts to be submitted specifically related to the biology of epithelial Na+ channels (ENaCs) and the actions of the hormone aldosterone.  This call for papers is in conjunction with the APS-sponsored 7th International Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels, which will be held on September 18-22, 2011. Submitted papers should address the central themes of ENaC, mineralocorticoid receptors and aldosterone signaling. Papers may focus on structure and regulation in normal and pathophysiologic states, or therapeutic interventions.

All papers will receive expedited review. Authors should indicate in their letter to the editor and in the online submission form under "Manuscript Type" that the submitted manuscript is in response to a Special Call for Papers. Accepted manuscripts will be published under a distinct heading and will receive special attention and handling. Only those papers not requiring extensive revision will be published under this call. If you currently have a manuscript on this topic that has already been submitted and would like it to be included in this Special Call, please contact Dr. Thomas Kleyman, Editor in Chief via e-mail at ajprenal@emory.edu.

GLUT1 enhances mTOR activity

In September's podcast Frank Brosius III (Michigan) discusses his group's recent work regarding a link between increases in cellular glucose uptake via Glut1 and activation of the mTOR signaling pathway. Join Editor in Chief Thomas Kleyman and Associate Editor Kumar Sharma as they discuss with Dr. Brosius cellular mechanisms of mTOR activation and the role of mTOR in glomerular hypertrophy and fibrosis in diabetes.

Carolyn L. Buller, Charles William Heilig, and Frank C. Brosius III. GLUT1 ENHANCES mTOR ACTIVITY INDEPENDENTLY OF TSC2 AND AMPK. Am J Physiol Renal Physiol, published ahead of print May 25, 2011, doi:10.1152/ajprenal.00472.2010.

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